Advancing your ADC Candidates Into the Clinic Faster with Improved Preclinical Models for Identifying Toxicity

Time: 9:00 am
day: Pre-Conference Day


A major challenge in ADC drug development is knowing what animal models will cross react with your ADC candidate, and how well these models will pick up toxicity to translate into your clinic which can cause costly and deadly delays to clinical programs. Take part in this deep dive session to learn all about in vivo model selection specific to your ADC candidates to identify potential safety concerns.

What this workshop will cover:

  • Outlining challenges in current in vivo model translatability and model selection for translatability of toxicities into humans
  • Setting up nonclinical safety studies with model selection in mind including in vitro designs
  • Understanding how to set up IND enabling safety studies to best support your clinical design