Translating In Vitro Toxicity Assays to Streamline ADC Development and Mitigate Toxicities

Time: 2:30 pm
day: Conference Day 1


  • Validating in vitro toxicity models allows for early identification and mitigation of potential adverse effects associated with ADC development.
  • Profiling toxicity across different concentrations provides insights into the cytotoxic effects of ADC candidates and may aid into dose optimization and risk assessment.
  • Investigating mechanistic insights sheds light on the underlying cellular and molecular pathways involved in ADC-induced toxicities, guiding the development of safer ADCs