Auristatin S: Developing an Auristatin Payload with Improved Tolerability & Modified Bystander Activity
9:30 am - Wednesday 26th August 2026
- Rationally designing Auristatin S to improve the tolerability of auristatin payloads through the tuning of permeability and bystander activity
- Explaining how Auristatin S maintains key auristatin properties, including strong tubulin binding affinity and induction of immunogenic cell death
- Exploring Auristatin S improved preclinical therapeutic window