Upcoming Meetings in the Series:

15th World ADC San Diego
November 4-7, 2024
San Diego, CA

4th ADC Target Selection Summit
December 10-12, 2024
San Diego, CA

15th World ADC London
March 3-6, 2025
London, UK

Improving Prediction & Translation of ADC Toxicities to Drive More Tolerable ADCs Successfully Into & Through Clinical Development

Welcome to the 2nd ADC Toxicity Summit

Preventing, Predicting and Mitigating ADC Toxicities

Toxicities continue to pose the most significant challenge in the progression of antibody-drug conjugates to the clinic, and with increasing companies entering into the ADC space and tackling toxicity, there is ever-increasing target and indication-competition. Considering the significant clinical setbacks witnessed in 2024, the demand to better understand the translatability of toxicities and develop more tolerable ADCs for achieving future clinical triumphs only grows stronger.

By addressing translational challenges and tackling off-target toxicities, the 2nd ADC Toxicity Summit returned at an imperative time to allow you to prevent, predict and mitigate toxicities to design and develop ADCs with a wider therapeutic index and progress them to the clinic.

In 2024, 80+ of your colleagues from Pfizer, Merck, ImmunoGen, Mersana, Daiichi Sankyo, AbbVie and more, united to discuss shared challenges with ADC toxicities from in vitro all the way to the clinic. Experts in toxicology and translational sciences disclosed never-heard before toxicity data, shared insights into optimal in vivo models for predictability, investigated the use of biomarkers for patient specific ADC prescription and introduced innovative strategies to transform the ADC landscape to increase therapeutic index.

Uniting the leading minds in ADC toxicology, offering actionable insights to unlock the full potential of predicting and mitigating toxicities in ADC development and addressing unmet needs head-on the summit provided three days of highly focused content. 

2024 Expert Speaker Faculty Included:

2023 Attendees Included:

ALX Oncology
Mersana Therapeutics
FDA
Mablink Bioscience Logo
Merck & Co
Immunogen
Loxo Oncology
bicycle-therapeutics-plc
Eli Lilly & Co.
Exelixis No B
Araris Logo (002)
Genmab
Tacalyx GmbH
Eisai
OBI Pharma
NGM Biopharmaceuticals Inc
Zymeworks
MBrace Therapeutics
Zentalis Pharmaceuticals
Angiex Inc. is a privately held biotech startup whose mission is to exploit newly discovered biological transport mechanisms to make drugs with revolutionary power over cancer. Based in Cambridge, Mass., Angiex was founded by a scientific team of leading experts in angiogenesis, vascular biology, and oncology.

What Your Peers Have to Say:

“Solving toxicity problems for ADCs has been a long standing challenge for new ADC developments. However, opportunities for experts to gather, discuss and share their expertise in the field of ADC toxicity has been scarce. Thus, this summit will be a wonderful chance for many ADC developers, including myself.”

Doo Young Jung, CEO & Founder, PinotBio

2024 Event Partners:

Part of the World ADC Series:

As part of the World ADC series - a platform that plows its collective energy into sourcing the insights you need. We investigate the most challenging problems facing the industry; source the leading experts who have game-changing solutions; and distill this into accessible formats of information exchange – for you. From globally leading conferences to webinars and industry reports, whatever the information you need,  ADC Toxicity Summit can offer you the insights you need to accelerate your ADC drug development into the clinic through to market.

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