Developing a Detailed Biorepository for Clinical Research in ADC Toxicity: Using Immunotherapy Toxicity Examples
- Applying large language models to capture and structure real-time toxicity events from clinical data sources, enabling more comprehensive and timely identification of ADC-related adverse events
- Developing a clinically annotated framework for systematic collection of patient samples across clinical trials and standard-of-care settings, supporting integrated analyses of ADC toxicity mechanisms
- Leveraging advanced analytical techniques to characterize toxicity profiles and compare them with analogous sporadic events, enabling deeper mechanistic insights and more informed strategies for toxicity prediction and management