Rethinking Peripheral Neuropathy Models: A Human Approach to Preclinical Testing
Time: 10:00 am
day: Scientific Program Day Two
Details:
- Preclinical drug development often fails due to poor translation from animal models to human physiology
- Peripheral neuropathy is difficult to assess using 2D cell cultures or animal models, as they fail to replicate 3D nerve structure and functional electrophysiology
- To address this, 28bio developed PNS-3D technology, a human, complex in vitro organoid model designed for preclinical testing of disease-, medication-, and toxin-induced neuropathies
