Predicting & Mitigating Toxicities Associated With Novel Payloads in ADC Development
Time: 9:02 am
day: Pre-Conference Workshop Day
Details:
As ADC development expands to new payload classes, understanding how to predict, minimize, and manage toxicity is critical for early-stage drug development.
This interactive workshop will provide hands-on discussions and case studies to help:
- Preview the current landscape of novel payloads in preclinical and clinical development
- Understand how novel payloads impact ADC toxicity? Exploring the mechanisms of emerging payload classes, including their on- and off-target toxicity risks
- Case Study: What can we learn from past ADC failures? – Reviewing clinical and preclinical toxicity data to identify early warning signals for payload-driven toxicities
- Interactive Discussion: What are the key challenges in predicting payload toxicities and how do we tailor the preclinical safety characterization for novel payloads?
