John Kwon

Company: AstraZeneca

Job title: Associate Director

Seminars:

Overcoming the Limitations of In Vitro Models to Predict ADC Toxicity 8:30 am

Exploring why in vitro efficacy and in vivo toxicity results often fail to correlate by discussing the disconnect between cytotoxicity assays and whole-organ toxicity and identifying better biomarkers for in vitro screening Discussing whether 2D monocultures are sufficient for predicting ADC-induced off-target toxicity, bystander effects, and immune-related toxicities Understanding the role computational modelling and AI…Read more

day: Scientific Program Day Two