Ronnie Yeager

Company: Abbvie

Job title: Project Director, Emerging Therapeutic Platforms Beacon

Seminars:

Implementing Rodent Models for ADC Payload Characterization to Support Discovery Screening & Inform on Pre-Clinical Species Relevance for Translation of Safety Profiles 9:30 am

Recapitulating clinically relevant ADC toxicity in an acute rodent IV infusion model for payloads to increase efficiency / reduce costs within discovery for payload screening Utilizing infusion models to better understand potential species-specific sensitivities to toxicities Giving Merit for infusion model to inform on anticipated ADC payload PK exposures respective of SOC / comparator drugs…Read more

day: Scientific Program Day One